Molecular weight (DA)
41kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RCL1. AA range:324-373
Specificity
RCL1 Polyclonal Antibody detects endogenous levels of RCL1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.,similarity:Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.,
Function
function:Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.,similarity:Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.,
Protein name
RNA 3'-terminal phosphate cyclase-like protein
Other name
RCL1; RNAC; RPC2; RPCL1; RTC2; HSPC338; RNA 3'-terminal phosphate cyclase-like protein
Fields
>>Ribosome biogenesis in eukaryotes
Human protein sequence Database
Q9Y2P8
Mouse protein sequence database
Q9JJT0
Rat protein sequence database
Cellular localization
Nucleus, nucleolus .
Tissue expression
Eye,Seminom,Umbilical cord blood,