Molecular weight (DA)
29kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RPS4Y1. AA range:214-263
Specificity
Ribosomal Protein S4Y1 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S4Y1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throug
Function
miscellaneous:This isoform is encoded on the Y chromosome.,similarity:Belongs to the ribosomal protein S4e family.,similarity:Contains 1 S4 RNA-binding domain.,
Protein name
40S ribosomal protein S4 Y isoform 1
Abbreviation
Ribosomal Protein S4Y1
Other name
RPS4Y1; RPS4Y; 40S ribosomal protein S4; Y isoform 1
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P22090
Mouse protein sequence database
Rat protein sequence database
Cellular localization
nucleus,nucleoplasm,cytosol,ribosome,polysome,membrane,cytosolic small ribosomal subunit,
Tissue expression
Coronary artery,Fetal liver,PCR rescued clones,Placenta,
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