Molecular weight (DA)
22kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SDC2. AA range:81-130
Specificity
Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008],
Function
function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,
Other name
SDC2; HSPG1; Syndecan-2; SYND2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD antigen CD362
Fields
>>Cell adhesion molecules;>>Malaria;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis
Human protein sequence Database
P34741
Mouse protein sequence database
P43407
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Brain,Embryo,Lung fibroblast,Muscle,Testis,
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