Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TRIP13. AA range:383-432
Specificity
TRIP13 Polyclonal Antibody detects endogenous levels of TRIP13 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009],
Function
similarity:Belongs to the AAA ATPase family.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. Interacts with HPV16 E1.,
Protein name
Pachytene checkpoint protein 2 homolog
Other name
TRIP13; PCH2; Pachytene checkpoint protein 2 homolog; Human papillomavirus type 16 E1 protein-binding protein; 16E1-BP; HPV16 E1 protein-binding protein; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-in
Human protein sequence Database
Q15645
Mouse protein sequence database
Q3UA06
Rat protein sequence database
Q5XHZ9
Cellular localization
male germ cell nucleus,nucleus,
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