Molecular weight (DA)
23 37kD
Immunogen
Synthesized peptide derived from human CATK (Cleaved-Ala115)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat CATK (Cleaved-Ala115, protein was cleaved amino acid sequence between 114-115 )
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
CTSK CTSO CTSO2
Protein name
CATK (Cleaved-Ala115)
Other name
Cathepsin K (EC 3.4.22.38;Cathepsin O;Cathepsin O2;Cathepsin X)
Fields
>>Lysosome;>>Apoptosis;>>Osteoclast differentiation;>>Toll-like receptor signaling pathway;>>Rheumatoid arthritis
Human protein sequence Database
P43235
Mouse protein sequence database
P55097
Rat protein sequence database
O35186
Cellular localization
Lysosome . Secreted . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells. .
Tissue expression
Predominantly expressed in osteoclasts (bones) (PubMed:7805878). Expressed in thyroid epithelial cells (PubMed:11082042).