Molecular weight (DA)
25kD
Immunogen
Synthesized peptide derived from human Kallikrein-7 (Cleaved-Ile30)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat Kallikrein-7 (Cleaved-Ile30, protein was cleaved amino acid sequence between 29-30 )
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
KLK7 PRSS6 SCCE
Protein name
Kallikrein-7 (Cleaved-Ile30)
Abbreviation
Kallikrein-7
Other name
Kallikrein-7 (hK7;EC 3.4.21.117;Serine protease 6;Stratum corneum chymotryptic enzyme;hSCCE)
Human protein sequence Database
P49862
Mouse protein sequence database
Q91VE3
Rat protein sequence database
P36373
Cellular localization
Secreted . In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front.
Tissue expression
Abundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level).
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