Molecular weight (DA)
32kD
Immunogen
Synthesized peptide derived from human PRSS8 (heavy chain, Cleaved-Ile45)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat PRSS8 (heavy chain, Cleaved-Ile45, protein was cleaved amino acid sequence between 44-45 )
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
PRSS8 (heavy chain, Cleaved-Ile45)
Other name
Prostasin (EC 3.4.21.-;Channel-activating protease 1;CAP1;Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain]
Human protein sequence Database
Q16651
Mouse protein sequence database
Q9ESD1
Rat protein sequence database
Q9ES87
Cellular localization
[Prostasin]: Cell membrane; Single-pass membrane protein.; [Prostasin light chain]: Secreted, extracellular space. Found in the seminal fluid. Secreted after cleavage of its C-terminus.; [Prostasin heavy chain]: Secreted, extracellular space. Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Tissue expression
Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
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