Molecular weight (DA)
56kD
Immunogen
Purified recombinant human SMYD1 protein fragments expressed in E.coli.
Specificity
This antibody detects endogenous levels of SMYD1 and does not cross-react with related proteins.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Background
function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 SET domain.,subunit:Interacts with HDAC1, HDAC2 and HDAC3.,
Function
function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 SET domain.,subunit:Interacts with HDAC1, HDAC2 and HDAC3.,
Other name
BOP;CD8 beta opposite;CD8b opposite;Histone lysine N methyltransferase SMYD1;KMT3D;SET and MYND domain-containing protein 1;SMYD1;SMYD1_HUMAN;Zinc finger MYND domain containing 18;ZMYND18;ZMYND22;zinc finger, MYND domain containing 18.
Fields
>>Lysine degradation;>>Metabolic pathways
Human protein sequence Database
Q8NB12
Mouse protein sequence database
P97443
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus .
Tissue expression
Expression seems mostly restricted to heart and skeletal muscle.
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