Immunogen
Purified recombinant H-FABP protein expressed in E.coli
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
ELISA 1:10000-20000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Background
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Function
domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
Other name
422 protein; Cardiac Fatty Acid Binding Protein; FABP 11; FABP 3; FABP11; FABP3; FABPH_HUMAN; fatty acid binding protein 11; Fatty acid binding protein 3; Fatty acid binding protein 3 muscle and heart; Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; Fatty acid binding protein 3 muscle; Fatty acid binding protein 3, muscle and heart (mammary derived growth inhibitor); Fatty acid binding protein 3, muscle; Fatty acid binding protein heart; Fatty acid binding protein, heart; Fatty acid binding protein, muscle and heart; Fatty acid binding protein, skeletal muscle; Fatty acid-binding protein 3; Fatty acid-binding protein; H FABP; H-FABP; heart; Heart type fatty acid binding protein; Heart-type fatty acid-binding protein; M FABP; M-FABP; mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid binding protein; Muscle fatty acid-binding protein; mylein protein P2 homolog; O FABP; OTTHUMP00000003898; P2 adopocyte protein.
Fields
>>PPAR signaling pathway
Human protein sequence Database
P05413
Mouse protein sequence database
P11404
Rat protein sequence database
Cellular localization
Cytoplasm.
Tissue expression
Fetal brain cortex,Heart,Liver,Mammary gland,Skeletal muscle,
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