Molecular weight (DA)
115kD
Immunogen
Synthesized peptide derived from human ERK5
Specificity
This antibody detects endogenous levels of ERK5 at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.79% sodium azide.
Dilution rate
IHC-p1:50-200 ,WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
ERK5, Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
Fields
>>MAPK signaling pathway;>>Gap junction;>>IL-17 signaling pathway;>>Neurotrophin signaling pathway;>>GnRH signaling pathway;>>Oxytocin signaling pathway;>>MicroRNAs in cancer;>>Fluid shear stress and atherosclerosis
Human protein sequence Database
Q13164
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm. Nucleus. Nucleus, PML body. Translocates to the nucleus upon activation.
Tissue expression
Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.
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