Molecular weight (DA)
121kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1110-1190
Specificity
KIF1C Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
kinesin family member 1C(KIF1C) Homo sapiens The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014],
Function
function:Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the kinesin-like protein family. Unc-104 subfamily.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Monomer .,tissue specificity:Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.,
Protein name
Kinesin-like protein KIF1C
Human protein sequence Database
O43896
Mouse protein sequence database
O35071
Rat protein sequence database
O35787
Cellular localization
Cytoplasm, cytoskeleton .
Tissue expression
Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.
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