Molecular weight (DA)
56kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Specificity
RBPJL Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function
function:Putative transcription factor, which cooperates with EBNA2 to activate transcription.,similarity:Belongs to the Su(H) family.,similarity:Contains 1 IPT/TIG domain.,subunit:Interacts weakly with EBNA2. Does not interact with any Notch proteins.,
Gene Name
RBPJL RBPL RBPSUHL
Protein name
Recombining binding protein suppressor of hairless-like protein (Transcription factor RBP-L)
Fields
>>Notch signaling pathway;>>Th1 and Th2 cell differentiation;>>Spinocerebellar ataxia;>>Human papillomavirus infection;>>Epstein-Barr virus infection;>>Viral carcinogenesis
Human protein sequence Database
Q9UBG7
Mouse protein sequence database
O08674
Rat protein sequence database
Cellular localization
Nucleus .
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