Molecular weight (DA)
22kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 90-170
Specificity
FGF21 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016],
Function
function:Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1, but not SLC2A4/GLUT4, expression.,similarity:Belongs to the heparin-binding growth factors family.,
Gene Name
FGF21 UNQ3115/PRO10196
Protein name
Fibroblast growth factor 21 (FGF-21)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>PI3K-Akt signaling pathway;>>Thermogenesis;>>Regulation of actin cytoskeleton;>>Pathways in cancer;>>Melanoma;>>Breast cancer;>>Gastric cancer
Human protein sequence Database
Q9NSA1
Mouse protein sequence database
Q9JJN1
Rat protein sequence database
Cellular localization
Secreted .
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