Molecular weight (DA)
47kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Specificity
KRT34 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008],
Function
caution:It is uncertain whether Met-1 or Met-43 is the initiator.,miscellaneous:There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).,similarity:Belongs to the intermediate filament family.,tissue specificity:Expressed in the hair follicle.,
Gene Name
KRT34 HHA4 HKA4 KRTHA4
Protein name
Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4) (Keratin-34) (K34)
Fields
>>Estrogen signaling pathway;>>Staphylococcus aureus infection
Human protein sequence Database
O76011
Mouse protein sequence database
Q9D646
Rat protein sequence database
Cellular localization
extracellular space,intermediate filament,extracellular exosome,
Tissue expression
Expressed in the hair follicles.
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