Molecular weight (DA)
50kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Specificity
KRT35 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008],
Function
miscellaneous:There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).,similarity:Belongs to the intermediate filament family.,tissue specificity:Early expression in the hair follicle, mainly found in supramatricial cells and lowermost cortical cells of the hair bulb.,
Gene Name
KRT35 HHA5 HKA5 KRTHA5
Protein name
Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5) (Keratin-35) (K35)
Fields
>>Estrogen signaling pathway;>>Staphylococcus aureus infection
Human protein sequence Database
Q92764
Mouse protein sequence database
Q497I4
Rat protein sequence database
Cellular localization
extracellular space,intermediate filament,extracellular exosome,
Tissue expression
Early expression in the hair follicle, mainly found in supramatricial cells and lowermost cortical cells of the hair bulb.
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