Molecular weight (DA)
22kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Specificity
MYL6B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
Function
function:Regulatory light chain of myosin. Does not bind calcium.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains.,
Protein name
Myosin light chain 6B (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa) (Smooth muscle and nonmuscle myosin light chain alkali 6B)
Fields
>>Vascular smooth muscle contraction;>>Tight junction;>>Oxytocin signaling pathway
Human protein sequence Database
P14649
Mouse protein sequence database
Q8CI43
Rat protein sequence database
Cellular localization
cytosol,muscle myosin complex,myosin complex,unconventional myosin complex,extracellular exosome,
Tissue expression
Brain,Ovary,Skeletal muscle,
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