Molecular weight (DA)
43kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
THIM Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.,pathway:Lipid metabolism; fatty acid metabolism.,similarity:Belongs to the thiolase family.,subunit:Homotetramer.,
Protein name
3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1)
Fields
>>Fatty acid elongation;>>Fatty acid degradation;>>Valine, leucine and isoleucine degradation;>>Metabolic pathways;>>Fatty acid metabolism
Human protein sequence Database
P42765
Mouse protein sequence database
Q8BWT1
Rat protein sequence database
P13437
Cellular localization
Mitochondrion .
Tissue expression
Adipocyte,Liver,Lung,
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