Molecular weight (DA)
34kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 240-320
Specificity
RLA0 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal pro
Function
function:Ribosomal protein P0 is the functional equivalent of E.coli protein L10.,similarity:Belongs to the ribosomal protein L10P family.,subunit:P0 forms a pentameric complex by interaction with dimers of P1 and P2.,subunit:P0 forms a pentameric complex by interaction with dimers of P1 and P2. Interacts with Lassa virus Z protein.,
Protein name
60S acidic ribosomal protein P0 (60S ribosomal protein L10E)
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P05388
Mouse protein sequence database
P14869
Rat protein sequence database
P19945
Cellular localization
Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:19188445, PubMed:17289661). .
Tissue expression
Adipose tissue,Brain,Cervix,Cervix carcinoma,Colon,Coronary
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