Molecular weight (DA)
80kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Specificity
CTNL1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,similarity:Belongs to the vinculin/alpha-catenin family.,subunit:Interacts with ARHGEF1.,tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,
Function
function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,similarity:Belongs to the vinculin/alpha-catenin family.,subunit:Interacts with ARHGEF1.,tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,
Protein name
Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)
Human protein sequence Database
Q9UBT7
Mouse protein sequence database
O88327
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein .
Tissue expression
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
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