Molecular weight (DA)
31kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 60-140
Specificity
AQP6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008],
Function
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,
Protein name
Aquaporin-6 (AQP-6) (Aquaporin-2-like) (Kidney-specific aquaporin) (hKID)
Human protein sequence Database
Q13520
Mouse protein sequence database
Q8C4A0
Rat protein sequence database
Q9WTY0
Cellular localization
Cytoplasmic vesicle membrane ; Multi-pass membrane protein .
Tissue expression
Kidney,Testis,
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