Molecular weight (DA)
68kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CTR3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein.[provided by RefSeq, May 2010],
Function
function:Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.,PTM:N-glycosylated.,similarity:Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.,tissue specificity:Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.,
Gene Name
SLC7A3 ATRC3 CAT3
Protein name
Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3)
Human protein sequence Database
Q8WY07
Mouse protein sequence database
P70423
Rat protein sequence database
O08812
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.
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