Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ACAP2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.,function:GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 1 BAR domain.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,tissue specificity:Widely expressed. Highest level in lung.,
Function
enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.,function:GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 1 BAR domain.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,tissue specificity:Widely expressed. Highest level in lung.,
Gene Name
ACAP2 CENTB2 KIAA0041
Protein name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
Human protein sequence Database
Q15057
Mouse protein sequence database
Q6ZQK5
Rat protein sequence database
Q5FVC7
Cellular localization
Endosome membrane ; Peripheral membrane protein .
Tissue expression
Widely expressed. Highest level in lung.
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