Molecular weight (DA)
65kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
DPOA2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
Function
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
Protein name
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)
Human protein sequence Database
Q14181
Mouse protein sequence database
P33611
Rat protein sequence database
O89043
Cellular localization
Nucleus.
Tissue expression
Cervix epithelium,Epithelium,Lung,
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