Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
G3PT Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic(GAPDHS) Homo sapiens This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008],
Function
catalytic activity:D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.,function:May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility.,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.,similarity:Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.,subunit:Homotetramer.,tissue specificity:Testis specific.,
Gene Name
GAPDHS GAPD2 GAPDH2 GAPDS HSD-35 HSD35
Protein name
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2) (Spermatogenic glyceraldehyde-3-phosphate deh
Fields
>>Glycolysis / Gluconeogenesis;>>Metabolic pathways
Human protein sequence Database
O14556
Mouse protein sequence database
Q64467
Rat protein sequence database
Q9ESV6
Cellular localization
Cytoplasm .
Tissue expression
Testis specific.
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