Molecular weight (DA)
41kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
GNA12 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
Function
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
Protein name
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Fields
>>MAPK signaling pathway;>>cGMP-PKG signaling pathway;>>Sphingolipid signaling pathway;>>Phospholipase D signaling pathway;>>Vascular smooth muscle contraction;>>Long-term depression;>>Regulation of actin cytoskeleton;>>Parathyroid hormone synthesis, secretion and action;>>Pathogenic Escherichia coli infection;>>Human cytomegalovirus infection;>>Pathways in cancer
Human protein sequence Database
Q03113
Mouse protein sequence database
P27600
Rat protein sequence database
Q63210
Cellular localization
Cell membrane ; Lipid-anchor . Lateral cell membrane ; Lipid-anchor . Cytoplasm . CDH1 enhances cell membrane localization. .
Tissue expression
Brain,Pancreas,Placenta,Uterus,
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