Molecular weight (DA)
101kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ICAM5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008],
Function
function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 9 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.,
Protein name
Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin)
Human protein sequence Database
Q9UMF0
Mouse protein sequence database
Q60625
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车