Molecular weight (DA)
55kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
KLDC5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,
Gene Name
KLHDC5 KIAA1340
Protein name
Kelch domain-containing protein 5
Human protein sequence Database
Q9P2K6
Mouse protein sequence database
Q8BFQ9
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton, spindle . Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis.
Tissue expression
Brain,Tongue,Uterus,
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