Molecular weight (DA)
29kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 450-530
Specificity
GPM6B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
glycoprotein M6B(GPM6B) Homo sapiens This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication. This protein may also be involved in osteoblast differentiation. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes Y and 22. [provided by RefSeq, Jan 2016],
Function
function:May be involved in neural development.,similarity:Belongs to the myelin proteolipid protein family.,tissue specificity:Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.,
Protein name
Neuronal membrane glycoprotein M6-b (M6b)
Human protein sequence Database
Q13491
Mouse protein sequence database
P35803
Rat protein sequence database
Q9JJK1
Cellular localization
Cell membrane ; Multi-pass membrane protein . Colocalizes with SERT at the plasma membrane. .
Tissue expression
Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.
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