Molecular weight (DA)
221kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 240-320
Specificity
NU205 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
nucleoporin 205(NUP205) Homo sapiens This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with steroid-resistant nephrotic syndrome. [provided by RefSeq, Jul 2016],
Function
subunit:Interacts with NUP93 and NUP35/NUP53.,
Gene Name
NUP205 C7orf14 KIAA0225
Protein name
Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205)
Fields
>>Nucleocytoplasmic transport;>>Amyotrophic lateral sclerosis
Human protein sequence Database
Q92621
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus membrane ; Peripheral membrane protein . Nucleus, nuclear pore complex . Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure. .
Tissue expression
Bone marrow,Breast,Clones donated by Kazusa DNA Research Inst.,Eye,Placenta,Pooled,Skin,