Molecular weight (DA)
27kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
PX11A Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012],
Function
function:May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane.,PTM:Seems not to be N-glycosylated.,similarity:Belongs to the peroxin-11 family.,subunit:Probably interacts with COPB2 and COPA (By similarity). Interacts with PEX19.,
Protein name
Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11-alpha)
Human protein sequence Database
O75192
Mouse protein sequence database
Q9Z211
Rat protein sequence database
O70597
Cellular localization
Peroxisome membrane ; Multi-pass membrane protein .
Tissue expression
Breast,Liver,Lung,PCR rescued clones,
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