Molecular weight (DA)
117kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Specificity
PCDH7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008],
Function
PTM:Isoform C is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 cadherin domains.,tissue specificity:Expressed predominantly in brain and heart and at lower levels in various other tissues.,
Protein name
Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)
Human protein sequence Database
O60245
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Single-pass type I membrane protein.
Tissue expression
Expressed predominantly in brain and heart and at lower levels in various other tissues.
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