Molecular weight (DA)
33kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Specificity
RSPH1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a male meiotic metaphase chromosome-associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia-24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014],
Function
function:May play an important role in male meiosis.,similarity:Contains 6 MORN repeats.,subcellular location:Cytoplasmic in late spermatocytes, secondary spermatocytes and round spermatids. Gathered around metaphase chromosomes during meiotic divisions.,tissue specificity:Testis specific.,
Gene Name
RSPH1 TSA2 TSGA2
Protein name
Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)
Human protein sequence Database
Q8WYR4
Mouse protein sequence database
Q8VIG3
Rat protein sequence database
Cellular localization
Cytoplasm . Cell projection, cilium . Cytoplasmic in late spermatocytes, secondary spermatocytes and round spermatids. Gathered around metaphase chromosomes during meiotic divisions (By similarity). .
Tissue expression
Expressed in trachea, lungs, airway brushings, and testes.
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