Molecular weight (DA)
194kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1560-1640
Specificity
RGPD5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
RANBP2-like and GRIP domain containing 5(RGPD5) Homo sapiens RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene shares a high degree of sequence identity with RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. It is believed that this RANBP2 gene family member arose from a duplication event 3 Mb distal to RANBP2. Alternative splicing has been observed for this locus and two variants are described. Additional splicing is suggested but complete sequence for further transcripts has not been determined. [provided by RefSeq, Jul 2008],
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,miscellaneous:One of the 8 copies of RANBP2 clustered close to the centromere of chromosome 2.,miscellaneous:One of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere.,similarity:Contains 1 GRIP domain.,similarity:Contains 2 RanBD1 domains.,similarity:Contains 2 TPR repeats.,similarity:Contains 3 TPR repeats.,tissue specificity:Expressed in testis.,
Gene Name
RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6
Protein name
RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63)
Human protein sequence Database
Q99666
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Expressed in testis.
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