Molecular weight (DA)
26kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Specificity
RASF3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003],
Function
caution:Has been termed RASSF5 by Ref.1.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subcellular location:Localized to microtubules in vascular endothelial cells.,tissue specificity:Widely expressed.,
Protein name
Ras association domain-containing protein 3
Human protein sequence Database
Q86WH2
Mouse protein sequence database
Q99P51
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton . Localized to microtubules in vascular endothelial cells.
Tissue expression
Widely expressed.
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