Molecular weight (DA)
52kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 410-490
Specificity
RGF1B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro).,induction:Up-regulated in monocytes stimulated with T.cruzi GPI-anchored mucins or bacterial lipopolysaccharide.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,
Function
function:Guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro).,induction:Up-regulated in monocytes stimulated with T.cruzi GPI-anchored mucins or bacterial lipopolysaccharide.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-GEF domain.,
Protein name
Ras-GEF domain-containing family member 1B (GPI gamma-4)
Human protein sequence Database
Q0VAM2
Mouse protein sequence database
Q8JZL7
Rat protein sequence database
Cellular localization
Early endosome . Late endosome . Midbody . May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase. .
Tissue expression
Blood,Teratocarcinoma,
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