Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Specificity
RRAGD Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
IP 1:50-200 WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004],
Function
function:Has guanine nucleotide-binding activity but lacks intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,
Protein name
Ras-related GTP-binding protein D (Rag D) (RagD)
Fields
>>Autophagy - animal;>>mTOR signaling pathway;>>Shigellosis
Human protein sequence Database
Q9NQL2
Mouse protein sequence database
Q7TT45
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .
Tissue expression
Amygdala,Lung,
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