Molecular weight (DA)
21kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Specificity
RB22A Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts directly with ZFYVE20 (By similarity). Binds EEA1.,
Protein name
Ras-related protein Rab-22A (Rab-22)
Human protein sequence Database
Q9UL26
Mouse protein sequence database
P35285
Rat protein sequence database
Cellular localization
Endosome membrane ; Lipid-anchor . Cell membrane ; Lipid-anchor . Early endosome . Late endosome . Cell projection, ruffle . Cytoplasmic vesicle . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus or M.tuberculosis. .
Tissue expression
Bladder,Colon,Colon carcinoma,Uterus,
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