Molecular weight (DA)
70kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 370-450
Specificity
RHG25 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008],
Function
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,
Gene Name
ARHGAP25 KIAA0053
Protein name
Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25)
Human protein sequence Database
P42331
Mouse protein sequence database
Q8BYW1
Rat protein sequence database
Cellular localization
cytosol,
Tissue expression
Blood,Bone marrow,Cord blood,Umbilical cord blood,
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