Molecular weight (DA)
80kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 250-330
Specificity
RHG28 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle.,
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle.,
Gene Name
ARHGAP28 KIAA1314
Protein name
Rho GTPase-activating protein 28 (Rho-type GTPase-activating protein 28)
Human protein sequence Database
Q9P2N2
Mouse protein sequence database
Q8BN58
Rat protein sequence database
Cellular localization
nucleoplasm,cytosol,integral component of membrane,cell junction,
Tissue expression
Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle.
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