Molecular weight (DA)
31kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Specificity
RHXF2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene, which encodes a transcriptional repressor, is one of two paralogous X-linked homeobox-containing genes and is highly expressed in a variety of cancers. In addition, the encoded protein associates with the cell membrane and with microtubules, and is concentrated at the leading edge of migratory cells. [provided by RefSeq, Dec 2015],
Function
similarity:Belongs to the paired-like homeobox family. PEPP subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Testis. Not detected in epididymis nor placenta.,
Gene Name
RHOXF2 PEPP2 THG1
Protein name
Rhox homeobox family member 2 (Paired-like homeobox protein PEPP-2) (Testis homeobox gene 1)
Human protein sequence Database
Q9BQY4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Testis. Not detected in epididymis nor placenta. In testis, mainly expressed in germ cells, but also detected in somatic cells such as Sertoli cells, Leydig cells and peritubular cells (PubMed:28171660).