Molecular weight (DA)
153kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 260-340
Specificity
RPAP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This protein forms part of the RNA polymerase II (RNAPII) enzyme complex and may recruit RNAPII to chromatin through its interaction with acetylated histones. [provided by RefSeq, Jul 2012],
Function
function:Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. Required for interaction of the RNA polymerase II complex with acetylated histone H3.,similarity:Belongs to the RPAP1 family.,subunit:Part of a RNA polymerase II complex that contains POLR2A, POLR2B, POLR2C, POLR2D, POLR2E, POLR2F, POLR2G, POLR2H, POLR2I, POLR2J, POLR2K, POLR2L, RPAP1, FCP1 plus the general transcription factors TFIIB and TFIIF.,
Protein name
RNA polymerase II-associated protein 1
Human protein sequence Database
Q9BWH6
Mouse protein sequence database
Q80TE0
Rat protein sequence database
Q3T1I9
Cellular localization
Nucleus .
Tissue expression
Brain,Epithelium,Eye,Mammary cancer,Teratocarcinoma,Testis,
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