Molecular weight (DA)
51kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CDK14 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008],
Function
similarity:Belongs to the protein kinase superfamily.,
Gene Name
CDK14 KIAA0834 PFTK1
Protein name
Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)
Fields
>>Transcriptional misregulation in cancer
Human protein sequence Database
O94921
Mouse protein sequence database
O35495
Rat protein sequence database
Cellular localization
Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Recruited to the cell membrane by CCNY.
Tissue expression
Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected.