Molecular weight (DA)
43kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SPB10 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015],
Function
function:Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Expressed specifically in the bone marrow.,
Protein name
Serpin B10 (Bomapin) (Peptidase inhibitor 10) (PI-10)
Human protein sequence Database
P48595
Mouse protein sequence database
Q8K1K6
Rat protein sequence database
Q8K3K4
Cellular localization
Nucleus. Cytoplasm. Mostly found in the nucleus.
Tissue expression
Expressed specifically in myeloid cells and the bone marrow.
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