Molecular weight (DA)
10kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
CCL1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014],
Function
function:Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.,induction:By PMA.,online information:CCL1 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,
Protein name
C-C motif chemokine 1 (Small-inducible cytokine A1) (T lymphocyte-secreted protein I-309)
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
Human protein sequence Database
P22362
Mouse protein sequence database
P10146
Rat protein sequence database
Cellular localization
Secreted.
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