Molecular weight (DA)
54kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SNPH Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Function
function:Inhibits SNARE complex formation by absorbing free syntaxin-1.,similarity:Belongs to the rad21 family.,subunit:Binds to syntaxin-1.,tissue specificity:Brain specific. Found in synapses.,
Human protein sequence Database
O15079
Mouse protein sequence database
Q80U23
Rat protein sequence database
B5DF41
Cellular localization
Membrane ; Single-pass membrane protein . Cell junction, synapse, synaptosome.
Tissue expression
Brain specific. Found in synapses.
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