Molecular weight (DA)
28kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
STX6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Involved in intracellular vesicle trafficking.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,subunit:Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3 (By similarity). Interacts with GOPC. Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.,
Function
function:Involved in intracellular vesicle trafficking.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,subunit:Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3 (By similarity). Interacts with GOPC. Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.,
Fields
>>SNARE interactions in vesicular transport
Human protein sequence Database
O43752
Mouse protein sequence database
Q9JKK1
Rat protein sequence database
Q63635
Cellular localization
Golgi apparatus membrane ; Single-pass type IV membrane protein .
Tissue expression
Brain,Muscle,
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