Molecular weight (DA)
142kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TENN Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Involved in neurite outgrowth and cell migration in hippocampal explants.,similarity:Belongs to the tenascin family.,similarity:Contains 1 fibrinogen C-terminal domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 9 fibronectin type-III domains.,
Function
function:Involved in neurite outgrowth and cell migration in hippocampal explants.,similarity:Belongs to the tenascin family.,similarity:Contains 1 fibrinogen C-terminal domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 9 fibronectin type-III domains.,
Protein name
Tenascin-N (TN-N)
Fields
>>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Human papillomavirus infection;>>MicroRNAs in cancer
Human protein sequence Database
Q9UQP3
Mouse protein sequence database
Q80Z71
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix .
Tissue expression
Not detected in normal adult mammary tissues or brain but expressed in most breast tumors and brain tumors, such as glioblastomas, astrocytomas and oligodendrogliomas, tested (PubMed:17909022, PubMed:19884327). In brain tumors, detected around the endothelial cell layer of the clood vessels (PubMed:19884327).
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