Molecular weight (DA)
83kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
S39A6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008],
Function
function:May act as a zinc-influx transporter.,induction:Up-regulated by estrogen in breast cancer cells lines.,PTM:N-glycosylated.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Highly expressed in the breast, protate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma.,
Gene Name
SLC39A6 LIV1 ZIP6
Protein name
Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6)
Fields
>>Alzheimer disease;>>Parkinson disease
Human protein sequence Database
Q13433
Mouse protein sequence database
Q8C145
Rat protein sequence database
Q4V887
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车