Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Specificity
MAGB6 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 MAGE domain.,tissue specificity:Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins.,
Protein name
Melanoma-associated antigen B6 (Cancer/testis antigen 3.4) (CT3.4) (MAGE-B6 antigen)
Human protein sequence Database
Q8N7X4
Mouse protein sequence database
Rat protein sequence database
Tissue expression
Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins.
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