Molecular weight (DA)
155kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
POGZ Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
pogo transposable element with ZNF domain(POGZ) Homo sapiens The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010],
Function
similarity:Contains 1 DDE domain.,similarity:Contains 1 HTH CENPB-type DNA-binding domain.,similarity:Contains 9 C2H2-type zinc fingers.,subunit:Interacts with Sp1.,
Gene Name
POGZ KIAA0461 SUHW5 ZNF280E ZNF635 Nbla00003
Protein name
Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635)
Human protein sequence Database
Q7Z3K3
Mouse protein sequence database
Q8BZH4
Rat protein sequence database
Cellular localization
Nucleus . Chromosome. Cytoplasm. According to some authors, it is not localized to mitotic chromatin (PubMed:19244240). Recruited to trimethylated 'Lys-9' of histone H3 (H3K9me3). .
Tissue expression
Brain,Colon,Epithelium,Neuroblastoma,Placenta,Retina,
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